Tag Archives | ART

HIV Meds and autopsy reviews in SA

Dr David Spencer,  Head, Infectious Diseases, Helen Joseph Hospital, Johannesburg Recent data from South African researchers indicate that HIV-infected people are surviving longer and that the spread of the virus among those ≤24 years may be decreasing. However, there are still areas of concern. Provided baseline CD4 counts at the time of ART initiation are […]

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A snapshot of HIV in SA

By Dr Catherine Elizabeth Martin, Programme Manager, Adult Care and Treatment, Wits Reproductive Health and HIV Institute  SA has the largest burden of HIV in the world. The total number of people living with HIV increased by over 1.5 million in the last decade to a current estimate of 5.7 million. The HIV prevalence has […]

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Viral resistance: where are we going in Africa?

By Dr Dave Spencer, Head, Infectious Diseases, Helen Joseph Hospital, Johannesburg More than eight million people in low- and middle-income countries are currently on antiretroviral therapy (ART). Approximately 2.1 million are in SA. Despite therapy, many still die. Of those who access ART, 5%-24% fail within 1-2 years. The success of therapy speaks for itself. But, in […]

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Managing Dyslipidaemia in the Individual Using Antiretroviral Therapy

Dr Steven Miller There is a greater risk of coronary hart disease among HIV-infected individuals. The reasons include traditional predisposing factors such as smoking, diabetes, dyslipidaemia and atherogenic diet as well as chronic immune activation and a prothrombotic state that frequently accompany HIV infection. Additional factors include endothelial dysfunction, and, possibly, certain antiretroviral agents (ARVs). […]

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Antiretroviral Therapy – Moving From Treatment to Prevention

Dr Steven Miller Since 2009, guidelines for initiating antiretroviral therapy (ART) in HIV-infected individuals have stressed the importance of commencing medication at a relatively well-preserved CD4 count (~350 cells/mm3). This strategy yielded significantly improved clinical outcomes. Since March 2012, guidelines in the US and several other countries now recommend considering ART for all HIV-infected people, […]

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Walking the HIV Care Pathway Together

Social Aspects of HIV/Aids Research in Africa Congress, Nelson Mandela Metropolitan University, Port Elizabeth 28 November – 2 December 2011 Dr Natasha Davies, Programme Advisor: adult care and treatment, Wits Reproductive Health and HIV Institute Over five million South Africans (>16% of all adults) are HIV-infected. Although over 1.4 million are enrolled in the world’s largest national antiretroviral therapy […]

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