Tag Archives | antiretroviral therapy

Cautious response to ‘functional cures’ for HIV

HIV clinicians have reacted with cautious interest to two March reports of ‘functional cures’, first of a baby in the US, then of a further 14 adult patients in a French study who received antiretroviral therapy (ART) shortly after infection and who later stopped treatment. Doctors at a Mississippi hospital administered triple therapy treatment to […]

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Time for New ARV Guidelines: The SA HIV Clinicians Society 2012 Guidelines

Dr Dave Spencer Nothing stays the same. Certainly not the HIV virus or its treatment. Failure of first-line antiretroviral therapy (ART) is 5% at 1-3 years. Approximately 20% of South African patients on ART are already on second-line therapies. A smaller number (4%-11% of those on second-line ART) require third-line drugs (unpublished data, Right to […]

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ART and Altered Distribution of Body Fat

Dr Steven Miller Altered body shape has been noted since the early days of antiretroviral therapy (ART) and is due to changes in body fat volume. Now known by the general, but nonspecific term ‘lipodystrophy’, it is a highly visible condition that is extremely distressing to those it affects. Lipodystrophy is frequently accompanied by a […]

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HIV Prevention in Key Populations

Dr Theo van den Handel As we move forward in the era of treating and managing HIV, the emphasis on prevention is becoming ever more important. It is frequently commented that we are not going to ‘treat our way out of this problem’. We need to focus on keeping those who are HIV negative free of […]

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The Changing Face of Crucial First-line Antiretroviral Therapy

Dr Steven Miller Research into the prognosis of people starting HIV treatment indicates that the risk of becoming very ill or dying from the disease within five years is linked to five key factors: having a CD4 count below 200/mm3, a viral load above 100 000 cp/ml at the time of starting treatment, being over 50 […]

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